Important
Questions Physiology (Nerve and Muscle)
Thought you would find these useful near profs :D
1.
Using your knowledge of Neuromuscular
transmission, explain why severe muscle weakness occurs in Myasthenia Gravis
and why Neostigmine improves muscle strength in this condition.
2.
Explain dif. Mechanisms for transport across
cell membrane.
3.
Discuss the role of different ions in genesis of
action potential. What is compound action potential?
4.
Describe secondary active transport.
5.
How RMP is generated and what is the role of
Sod-Pot pump in this regard
6.
A 20 year old female comes with bilateral
ptosis, proximal muscle weakness and she also complains that she cannot comb
her hair. She also complains of difficulty in chewing, swallowing and walking.
a. Give your diagnosis with brief description
b. What is Lambert-Eaton syndrome and its treatment
a. Give your diagnosis with brief description
b. What is Lambert-Eaton syndrome and its treatment
c. Give sequence of events of power stroke
d. Write difference between fast vs slow
muscle fibers.
7.
Give mechanism of genesis of resting membrane
potential. What is the effect of hyperkalemia on this potential?
8.
Draw and explain the compound action potential.
9.
What is end plate potential? What changes occur
in it in Myasthenia Gravis?
10.
Write explanatory notes on:
a.
Troponin-tropomyosin complex
b.
Rigor mortis
c.
Genesis of RMP
11.
Draw and label strength duration curve.
12.
Explain various properties of nerve fibers
13.
How neuromuscular transmission can be blocked?
Give the mechanism of blockage of each.
14.
Compare and contrast visceral and multiunit type
of smooth muscle
15.
Write and account of excitation-contraction
coupling.
16.
What are sources of ATP in skeletal muscle
contraction?
17.
Write a note on Wallerian degeneration.
18.
Describe mechanism and characteristics of smooth
muscle contraction.